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婦懷葡萄胎 精子惹的禍

一名廿五歲女子甫從國外歸來,因為月經過期、陰道出血及腹脹三個多月到台南市郭綜合醫院求診,經婦科主任李耀泰診斷為葡萄胎,術後恢復良好,一個月後月經來臨,且血清絨毛膜指數已接近正常值,至今持續追蹤。 李耀泰表普騰服務站示,兩隻精子同時進入一空的卵子內,便會發育成葡萄胎,葡萄胎約九成的染色體為46XX和十成的46XY,而其X和Y染色體皆來自父系精子,但細胞質中的粒線體則全為母親來源。 李耀泰表示,這名婦女案例,經由子宮內容物,LG服務站進行染色體分析,結果歌林服務站為國際牌服務站46XX,基因分析證明兩條X染色體均源自父親。 李耀泰表示,葡萄胎最常臨床表現,包括陰道出血、嚴重噁心和嘔吐、子宮腫大超過懷孕週數、兩側卵巢腫大,甲狀腺功能過高和早期產生之子癲前症。 李耀泰表示,超音波可見整個子宮內呈暴風雪狀,主要是因水腫的絨毛加血塊所致,沒有看到胎兒的影像,血液中絨毛膜指數(hCG)很高,半數患者在每西西十萬單位以上,但該病患特徵,七百餘萬單位的血清絨毛膜指數極高,實屬罕見。

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